Seeing a dog with a distended stomach, unproductive attempts at vomiting, weakness, and rapid, strained breathing is sure to strike fear into the heart of any dog breeder or owner. These classic signs of gastric dilatation and volvulus (GDV) or “bloat” as it is colloquially known, are the worst enemy of anyone who has experienced this traumatic, life-threatening condition that often affects otherwise healthy dogs. The significance of the heartbreak caused by this disease has been made obvious to me by the numerous clients that have inquired about genetic testing for this condition at Paw Print Genetics. Though many suspects have been implicated in the cause of GDV in our dogs, unfortunately no single risk factor, including a genetic mutation, can adequately explain the lion’s share of cases at this point. With an estimated 21-24% chance of large and giant breed dogs developing GDV within their lifetime (Broome and Walsh 2003), it is no surprise that people would love to find an easy, low-cost and predictable way to prevent this disease.
GDV is a condition marked by rotation of the stomach on the upper end near the esophagus. This rotation closes off the opening between the stomach and esophagus, thus ...
