Author archives: Lisa Shaffer

At Paw Print Genetics, we are often asked about a common scenario, “My bitch is about ready to whelp and I just found out that her half-sister carries this horrible genetic disease. What should I do?”. Our answer is always the same. Follow these simple steps to avoid this situation while saving you time, money and anguish in the future:

1. Test your dam and sire with the breed-specific panel before you breed. 

Performing a complete, breed-specific panel on your dam and sire will help you make an informed decision to breed or not to breed.

Testing first the dam and sire with an entire panel also saves money in the long run by reducing the need to test their future puppies. This is because puppies will be clear for a disease if both tested parents are also clear for that disease. Therefore, the puppies sold as future breeding stock will only need to be tested for any disease-causing mutations found in the parents. If both parents are clear of all disease-causing mutations, no testing of the puppies is necessary.

2. Test your new puppy with the entire breed-specific panel before you buy.

Introducing a new dog into ...

Bringing a new puppy into the family is a financial and emotional investment.  Once the kids fall in love with that new puppy, there is no turning back, no matter what might happen.  Whether you are a professional dog breeder or simply a careful buyer, genetic testing can help you understand the potential genetic threats to your dog’s health. It will also inform you of potential inherited diseases that may get passed on if you decide to breed. By testing both the dam and sire, this information will help you select the proper mate to produce the healthiest puppies thereby increasing the value of your breeding program.  If both the dam and sire are clear, all of the puppies will be clear by parentage. Thus, those that are diligent about testing will save money over time. However, every time a new dog is brought into a breeding program, that dog should be screened for all known disease mutations to make sure you are not introducing new mutations into your lines.

Paw Print Genetics was founded by geneticists and veterinarians committed to quality genetic testing and outstanding customer service. Paw Print Genetics offers the largest selection of tests ...

Degenerative myelopathy (DM) can be a devastating disease. Some breeds with this disease will lose the ability to walk in their later years – certainly after the age most dogs are bred. The mutation has been found in more than 120 breeds (1), which indicates that the original mutation might have occurred hundreds or thousands of years before many of the modern dog breeds emerged.

However, the frequency of the mutation varies between breeds and certainly the risk of developing the clinical disease seems quite distinct and breed-specific. For example, the frequency of carriers and homozygous mutation (affected) dogs in the Kerry blue terrier is about 52%(1), while carriers and affected dogs make up 91% of Pembroke Welsh corgis in Japan(2). Although wire fox terriers have a similar combined carrier and at-risk frequency of 90%, none have ever developed the clinical signs of DM(3).

In a 2001 study by Moore et al., German shepherd dogs had nearly twice the risk for death associated with spinal cord diseases, compared with Belgian shepherd dogs among military dogs(4).  Although we don’t know for sure if the spinal cord disease was DM, certainly DM is one of the more common causes of this ...

The United States Border Collie Handler’s Association (USBCHA) holds an annual event to find the best of the best herding dogs. The USBCHA is the sanctioning body for sheep and cattledog trials throughout the United States and Canada. Founded in 1979, the USBCHA has grown into an organization of more than 800 members. Members who qualify at sanctioned open trials during the year are eligible to compete in the USBCHA National Sheep and Cattle Dog Finals to determine the champion open dog and handler for that year. The first Sheep Dog Finals were held in 1979 with the first National Cattledog Finals held in 2001.  This year, the finals will be held at the Strang Ranch in Carbondale, Co September 8-14, 2014. The 460 acre ranch is at an altitude of 7000 feet and offers stunning views of Mount Sopris and the Elk Mountain Range in Western Colorado.

Paw Print Genetics will be on-hand to answer questions about genetic screening for Border Collies and other herding dogs.  Paw Print Genetics and the USBCHA have partnered to help educate its members about inherited diseases and to provide discounts to the USBCHA members.  Working dogs are an investment and ...

Paw Print Genetics will be attending two events in the month of August.  First, you will find our booth at the Olympic Kennel Club show at the Enumclaw Expo Center August 14-17. 2014.  Specialties include the Rainier Sporting Dog Association, Samoyed, Keeshond, Chihuahua, German shorthaired pointers and English cocker spaniels, among many others. The Olympic Kennel Club was formed in 1944 after the end of World War II.  This all breed show attracts about 3,000 participants and visitors during four days.  Stop by the Paw Print Genetics booth. We will have discounted testing during the weekend and can even swab your dog while you enjoy the show.

Since 1982, Game Fair has been held in Ramsey, MN and Paw Print Genetics will be there.  During two weekends in August, more than 20,000 people visit the 80-acre site outside Anoka, MN.  August 8, 9, 10 and 15, 16, and 17 will be days filled with archery, dog events, goose and turkey calling, and even a taxidermy competition.  Have fun while you learn about canine genetics listening to our seminar What do you know about your dog's genetics? on one of ...

In October of last year, we told you the story of Rickie Roo, the amazing agility dog, service dog and a roving reporter for the United States Dog Agility Association. She is well known in the sport of agility and in the rat terrier community.

On October 12^th, 2013, Roo unfortunately had to have emergency surgery because of a luxated lens in her left eye. Primary Lens Luxation, or PLL, is a condition that can happen in many breeds including American Eskimo dog, American hairless terrier, Australian cattle dog, border collie, bull terrier, Chinese crested, Jack Russell terrier, jagdterrier, Lakeland terrier, Lancashire heeler, miniature bull terrier, Norwich terrier, Parson Russell terrier, Patterdale terrier, rat terrier, Russell terrier, Sealyham terrier, Teddy Roosevelt terrier, Tenterfield terrier, Tibetan terrier, toy fox terrier, Volpino Italiano, Welsh terrier, wire fox terrier and Yorkshire terrier.

Lens luxation can happen suddenly and when it occurs, needs to be surgically corrected as soon as possible to try to minimize any loss of sight. Luckily, Rickie Roo's luxated lens was caught very early by ...

I recently took a trip to Colorado Springs to visit colleges with my son. I enjoyed spending time with him and visiting Colorado College. We were very impressed with the student-led information session and campus tour. The students were knowledgeable, poised, enthusiastic and inviting. If these undergraduates are a reflection of the school and its caliber of students and faculty, then I know that my son will do well there. We left with an overwhelmingly positive impression of the school, the campus and the region. I would give our student ambassadors an A-plus for customer service during our visit. However, during our trip we were customers of several other companies and many of them fell short of superior, or even acceptable, customer service.

Our flight to Colorado Springs was uneventful and the staff of United Airlines did an exceptional job in making us feel special and that they appreciated our business. However, when we landed in Colorado Springs, things started to fall apart.

We arrived promptly at the Hertz counter to find that the car we had reserved and paid for weeks in advance had been given to someone else. Hertz claimed to have no cars to rent to us ...

It is hard to believe that it has been a year since Paw Print Genetics opened its doors and started offering its testing service.  A lot has happened since then.  Prior to offering our testing services for inherited diseases of canines, we had a lot of work to do. We spent many weeks combing the medical literature with the goal of identifying all of the disease mutations associated with medical problems in dogs. After the mutations were identified in the public literature, we developed the tests that showed whether a dog had the normal or mutated DNA sequence. 

For each mutation, two different tests were developed, so that each DNA sequence is examined two times in two different ways. This is how we achieved 100% accuracy and 100% reliability with our testing.  Once the two tests were developed, we then validated the tests. To do this, we enlisted the help from many of our current customers to provide samples on dogs that were known normal, carriers or affected with the diseases for which we developed tests. The results from these samples were submitted to the laboratory directors, PhD geneticists and licensed veterinarians, for review of the data without ...

The pointing Labrador is just one of many exceptional dog breeds. Versatile in their ability to point, flush and retrieve, pointing Labradors may be the perfect hunting companion.  How a specific dog breed has so many desirable characteristics is not a mystery. All domesticated dogs were bred for specific behavioral or physical traits that were required for certain jobs – whether it was for chasing and catching varmints, retrieving the evening’s dinner, or bringing in the herd, dogs are the perfect species for a variety of tasks.  

All of these traits, behavioral and physical, have a genetic component and are determined by an accumulation of genes with modifications, or mutations, that result in some outcome. Whether the traits are pointing, coat color or skull structure, humans chose founding stock to create the various breeds and bred these dogs for the traits they desired.  However, undesirable, even harmful genetic mutations were carried along in these breeds. The most ancient mutations can be found in many breeds of dogs, whereas those mutations that arose more recently maybe found in only one or two breeds.

With the advent of molecular genetic technologies and the sequencing of the domestic dog (Canis ...

Paw Print Genetics often gets asked about an optimal time to swab a new litter of puppies. When reviewing these tips, please keep in mind that it can take up to two weeks to obtain results once Paw Print Genetics has received the swabs.  Therefore, allow plenty of time for the laboratory to process your samples before promising a specific date that the puppy can join its new home.

Puppies and dogs can be tested at any age. However, it is a good idea to allow the puppies to stabilize after birth, bond with their mother, and demonstrate that they can feed and grow before testing.  You do not have to wait until the puppies are weaned; once the puppies are stable and thriving, they can be swabbed.  For puppies that are not weaned, the puppies should be separated from their mother for at least two hours prior to swabbing. This is to ensure we get the DNA of the puppy instead of the mom's DNA. During this time, they should have plenty of water and should not be allowed food to avoid contamination of samples. Once the swabbing is completed, the pups can rejoin their ...